Organism-on-chip technology
in vivo testing at the in vitro scale
INTRODUCING THE FIRST ORGANISM-ON-CHIP TECHNOLOGY
ENABLING 3rs FULL-ORGANISM TESTING
Automated end-to-end culture, treatment, imaging and analysis
SydLab™ One combines the unique Organism-on-Chip technology with robotics and high-content imaging to make all the C. elegans experimentation processes automated.
Patented MWM technology
Thanks to the development of our patented Microfluidic Worm Matrices (MWM) technology, we offer the possibility of confining worms within large arrays of microfluidic chambers in a simple, fast and reproducible way, by means of passive hydrodynamic worm-valves.
First Organism-on-chip
By the usage of our MWM method, the Nagi team was eble to develop a myth that today is a reality: the first Organism-on-Chip technology for the controlled growth of C. elegans and their automated time-resolved treatment and analysis, throughout their entire lifespan.
From a chip to a full system
Thanks to the scalability and ease of use of the Nagi chips, today we present the full end-to-end solution for high-content screening of substances on micro-organisms: SydLab™ One.
EXPLORE SYDLAB ONE
Inside the nagi chips
discover the secrets of the first organism-on-chip
No more messy plates. No more manual handling. Unlock the full potential of small organisms with the microfluidic Nagi™ Chips. More parallel conditions, more readouts, more possibilities. All compatible with the SydLab™ One products.
Sydlab™ One: One device. infinite possibilities.
Get whole-organism readouts like never before
SydLab™ One can run tests on up to four Nagi™ Chips in parallel, where 1000+ individual micro-organisms are automatically confined, cultured, treated, and studied via time-lapse microscopy images and videos at unprecedented throughput and over long-term time-resolved experiments.
Combining cutting-edge high-content screening technology and robotics, SydLab™ One is the first all-in-one benchtop laboratory device capable of performing multiple bioassays and wide screenings of your compounds of interest on micro-organisms.
Brightfield imaging
Fluorescence imaging
MotilitY videos
Explore the data
whole-organism phenotypic readouts instantly
SydLab™ One solution counts with the AI-powered imaging extraction and real-time SydLab™ Analyzer: a software suite trained to support scientists at every step of the process. From experiment design to readouts extraction, all in just a user optimized software.
Welcome to the era of automated multi-phenotypic data extraction, analysis and interpretation on small organisms.
welcome to the sydlab™ one universe
nagi Resources
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Publication
Integrated Microfluidic Device for Drug Studies of Early C. elegans Embryogenesis.
Journal: Advanced Science
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Publication
Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models.
Journal: Molecular Neurodegeneration
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Publication
An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging.
Journal: Scientific Reports
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Publication
A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans.
Journal: Nature Protocols
Meet our technology here
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The Explainable AI in Biology Conference (#XAIB24)
17 Oct 24The Explainable AI in Biology Conference (#XAIB24)
17 Oct 24The Explainable AI in Biology Conference #XAIB24 is dedicated to exploring the latest advancements in applying explainable and responsible AI techniques to genomics and biology, making it the perfect venue for discussing our work at Nagi Bioscience. Attend our poster presentation where we showcase how we use ML-based image analysis and AI to streamline ageing studies in C. elegans by end-to-end automated high-throughput analysis on our platform SydLab™ One. Download the poster here.
Download our poster -
ForumEPFL 2024
8 Oct 24ForumEPFL 2024
8 Oct 24Are you interested in life science technologies and want to make an impact in replacing and reducing animal testing? Join us at Forum EPFL next Tuesday 8th October! We are looking for talented and motivated people to be part of the Nagi team! Take a look at our internship opportunities, leave your CV, chat with us, and get to know first-hand our pioneer technology for small organisms testing.
The place to be? Nagi Bioscience’s booth! Together for a new era in biological testing. #inwormwetrust
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ILMAC Lausanne 2024
18 Sep 24ILMAC Lausanne 2024
18 Sep 24Join us at Ilmac Lausanne 18th-19th September 2024! We will be showcasing our innovative SydLab™ One platform at our friends’ booth BioAlps (Swiss Health Valley). Discover how our fully automated, AI-powered platform is revolutionizing lab automation and biological testing.
Bonus! Don’t miss our CEO’s Matteo Cornaglia’s pitch Thursday 19th at 1:30pm. Some interesting SydLab™ One use cases are waiting for you. We can’t wait to connect with you at ILMAC! For further information, contact us at info@nagibio.ch.
Nagi Bioscience at ILMAC 2024