Organism-on-chip technology
in vivo testing at the in vitro scale
INTRODUCING THE FIRST ORGANISM-ON-CHIP TECHNOLOGY
ENABLING 3rs FULL-ORGANISM TESTING
Automated end-to-end culture, treatment, imaging and analysis
SydLab™ One combines the unique Organism-on-Chip technology with robotics and high-content imaging to make all the C. elegans experimentation processes automated.
Patented MWM technology
Thanks to the development of our patented Microfluidic Worm Matrices (MWM) technology, we offer the possibility of confining worms within large arrays of microfluidic chambers in a simple, fast and reproducible way, by means of passive hydrodynamic worm-valves.
First Organism-on-chip
By the usage of our MWM method, the Nagi team was eble to develop a myth that today is a reality: the first Organism-on-Chip technology for the controlled growth of C. elegans and their automated time-resolved treatment and analysis, throughout their entire lifespan.
From a chip to a full system
Thanks to the scalability and ease of use of the Nagi chips, today we present the full end-to-end solution for high-content screening of substances on micro-organisms: SydLab™ One.
EXPLORE SYDLAB ONE
Inside the nagi chips
discover the secrets of the first organism-on-chip
No more messy plates. No more manual handling. Unlock the full potential of small organisms with the microfluidic Nagi™ Chips. More parallel conditions, more readouts, more possibilities. All compatible with the SydLab™ One products.
Sydlab™ One: One device. infinite possibilities.
Get whole-organism readouts like never before
SydLab™ One can run tests on up to four Nagi™ Chips in parallel, where 1000+ individual micro-organisms are automatically confined, cultured, treated, and studied via time-lapse microscopy images and videos at unprecedented throughput and over long-term time-resolved experiments.
Combining cutting-edge high-content screening technology and robotics, SydLab™ One is the first all-in-one benchtop laboratory device capable of performing multiple bioassays and wide screenings of your compounds of interest on micro-organisms.
Brightfield imaging
Fluorescence imaging
MotilitY videos
Explore the data
whole-organism phenotypic readouts instantly
SydLab™ One solution counts with the AI-powered imaging extraction and real-time SydLab™ Analyzer: a software suite trained to support scientists at every step of the process. From experiment design to readouts extraction, all in just a user optimized software.
Welcome to the era of automated multi-phenotypic data extraction, analysis and interpretation on small organisms.
welcome to the sydlab™ one universe
nagi Resources
-
Publication
Integrated Microfluidic Device for Drug Studies of Early C. elegans Embryogenesis.
Journal: Advanced Science
-
Publication
Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models.
Journal: Molecular Neurodegeneration
-
Publication
An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging.
Journal: Scientific Reports
-
Publication
A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans.
Journal: Nature Protocols
Meet our technology here
-
Bio-Europe Spring 2024
18 Mar 24Bio-Europe Spring 2024
18 Mar 24Nagi Bioscience is attending once again Bio-Europe Spring! Join us in Barcelona March 18-20, 2024. Connect with us via PartneringONE and get to know first hand the first fully automated Organism-on-Chip technology to speed-up and de-risk your discovery efforts.
Know more about our technologies -
SOT and ToxExpo 2024
10 Mar 24SOT and ToxExpo 2024
10 Mar 24SOT and ToxExpo, the annual landmark toxicology conference, is returning to Salt Lake City, 10th-14th March. Meet the Nagi Bioscience team at booth #535 and get to know SydLab™ One, the laboratory technology revolutionizing safety and efficacy assessment: high-throughput, fast, cost-saving and providing whole-organism smart data without the use of vertebrates. Curious? Download the product brochure and have a sneak peek.
SOT & ToxExpo -
The Allied Genetics Conference – TAGC24
6 Mar 24The Allied Genetics Conference – TAGC24
6 Mar 24Meet Nagi Bioscience and our laboratory system SydLab™ One for fully automated C. elegans experimentation at TAGc24, 6th-10th March in Washington, DC. Pass by the booth #633 and witness how SydLab™ One handles autonomously culture, treatment, imaging, and AI-based analysis of 64 independent worm populations and conditions.
TAGC is Genetics Society America’s flagship conference that brings together scientists from multiple international biological research communities (C. elegans, Drosophila, Zebrafish, etc.) to share cutting-edge science, foster new collaborations, and strengthen existing relationships.
TAGC24