Organism-on-chip technology
in vivo testing at the in vitro scale
INTRODUCING THE FIRST ORGANISM-ON-CHIP TECHNOLOGY
ENABLING 3rs FULL-ORGANISM TESTING
Automated end-to-end culture, treatment, imaging and analysis
SydLab™ One combines the unique Organism-on-Chip technology with robotics and high-content imaging to make all the C. elegans experimentation processes automated.
Patented MWM technology
Thanks to the development of our patented Microfluidic Worm Matrices (MWM) technology, we offer the possibility of confining worms within large arrays of microfluidic chambers in a simple, fast and reproducible way, by means of passive hydrodynamic worm-valves.
First Organism-on-chip
By the usage of our MWM method, the Nagi team was eble to develop a myth that today is a reality: the first Organism-on-Chip technology for the controlled growth of C. elegans and their automated time-resolved treatment and analysis, throughout their entire lifespan.
From a chip to a full system
Thanks to the scalability and ease of use of the Nagi chips, today we present the full end-to-end solution for high-content screening of substances on micro-organisms: SydLab™ One.
EXPLORE SYDLAB ONE
Inside the nagi chips
discover the secrets of the first organism-on-chip
No more messy plates. No more manual handling. Unlock the full potential of small organisms with the microfluidic Nagi™ Chips. More parallel conditions, more readouts, more possibilities. All compatible with the SydLab™ One products.
Sydlab™ One: One device. infinite possibilities.
Get whole-organism readouts like never before
SydLab™ One can run tests on up to four Nagi™ Chips in parallel, where 1000+ individual micro-organisms are automatically confined, cultured, treated, and studied via time-lapse microscopy images and videos at unprecedented throughput and over long-term time-resolved experiments.
Combining cutting-edge high-content screening technology and robotics, SydLab™ One is the first all-in-one benchtop laboratory device capable of performing multiple bioassays and wide screenings of your compounds of interest on micro-organisms.
Brightfield imaging
Fluorescence imaging
MotilitY videos
Explore the data
whole-organism phenotypic readouts instantly
SydLab™ One solution counts with the AI-powered imaging extraction and real-time SydLab™ Analyzer: a software suite trained to support scientists at every step of the process. From experiment design to readouts extraction, all in just a user optimized software.
Welcome to the era of automated multi-phenotypic data extraction, analysis and interpretation on small organisms.
welcome to the sydlab™ one universe
nagi Resources
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Publication
Integrated Microfluidic Device for Drug Studies of Early C. elegans Embryogenesis.
Journal: Advanced Science
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Publication
Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models.
Journal: Molecular Neurodegeneration
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Publication
An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging.
Journal: Scientific Reports
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Publication
A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans.
Journal: Nature Protocols
Meet our technology here
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Swiss Biotech Day 2024
22 Apr 24Swiss Biotech Day 2024
22 Apr 24Join Nagi Bioscience at the Swiss Biotech Day 2024 April 22-23rd in Basel !Connect with our experts on-site and check novel data generated by our high-content screening platform SydLab™ One at the poster presentation. What to expect? SydLab™ One featuring DART, mitocondrial stress response, our lifespan and healthspan assay and molecular mechanisms of aging readouts. Do not miss our talk “SydLab™ One: Accelerating drug discovery with fully automated Organism-on-Chip testing” April 23rd, 1pm at Room Rio.
SBD 2024 -
Ver Midi XXV
3 Apr 24Ver Midi XXV
3 Apr 24Join us at the Annual Meeting of Researchers using C. elegans and other nematodes in Lyon, France. Explore exclusive data generated by our laboratory technology SydLab™ One for fully automated C. elegans experimentation at the Nagi booth! See you there!
Ver Midi XXV -
ForumLabo 2024
27 Mar 24ForumLabo 2024
27 Mar 24Meet Nagi Bioscience and our latest innovation SydLab™ One for fully automated high-content screening of drugs and chemicals on C. elegans nematodes. Elevate and de-risk your safety and efficacy assessment of your candidates in an effective and fast manner. Pass by our booth F43, check our innovation at the Couloir de l’Innovation expo, or attend our session “Lab automation and new technologies” by ELRIG.fr
Nagi at ForumLabo 2024