Microbiome studies

Using an in vivo model and cutting-edge technology, Nagi Bioscience empowers researchers to delve deeper into microbiome studies, delivering precise and actionable insights into host-microbe interactions. Our solution enables ethical, efficient testing of microbial treatments, providing valuable data on microbiome-related pathways and their impact on health and disease. With a streamlined workflow, Nagi Bioscience accelerates the exploration, development, and de-risking of microbiome-based therapies, ultimately advancing scientific understanding and promoting innovative solutions for improved health outcomes.

C. elegans: A gateway to microbiome studies

Caenorhabditis elegans is a versatile and well-established model for microbiome research, offering unique advantages for studying host-microbe interactions. With a simple, well-characterized microbiome and a fully mapped genome, C. elegans enables the exploration of how microbial communities influence host physiology, and disease. Its short lifespan, ease of genetic manipulation, and high-throughput screening potential make it ideal for studying the impact of microbiota on health, aging and disease.

Research using C. elegans has provided valuable insights into microbiome-induced inflammation and metabolic regulation, contributing to the development of microbiome-based therapies. In summary, C. elegans serves as an efficient and translationally relevant model to accelerate microbiome research and therapeutic innovation.

C. elegans inside a chamber of a Nagi Bioscience’s microfludic Organism-on-Chip.

In vivo results, at in vitro scale.

Our standardized protocols and automated workflow ensure consistent, actionable results.

to support your publications.

The powerful C. elegans model delivers high translational value, making it a proven cornerstone in research.

Fluorescence markers can be easily monitored and quantified for functional studies and identification of mechanism of action. Disease models can also be used (rare diseases, infectious diseases, metabolic diseases).

The advanced high-content imaging of our SydLab™ One platform enables the visualization and analysis of diverse phenotypes, supporting wider range of applications.


Readouts

  • Growth dynamics and parameters.
  • Healthspan: Reproductive, Motility, Intestinal Atrophy.
  • Lifespan: Survival.
  • Fluorescence: Functional, Mechanism of Action.
Erez Aminov

We are very pleased with the experience of the Nagi Bioscience team and the exceptional quality of their work. Their innovative technology has been instrumental in allowing us to gather critical scientific data quickly, providing invaluable insights that significantly advance our research in longevity.

Erez Aminov

CEO, Telomir Pharmaceuticals, Inc.

Prof. Konstantinos Palikaras, PhD

By improving precision and enhancing reproducibility, SydLab™ One empower us to explore new frontiers in critical fields of medical science. We are excited to leverage this fully automated, end-to-end solution in our projects.

Prof. Konstantinos Palikaras, PhD

Group Leader of the Unit of Neurogenetics and Ageing, Laboratory of Physiology, University of Athens (NKUA)

Our commitment to you and your team

At Nagi Bioscience, we are more than just a service laboratory. We are a strategic partner dedicated to your success. Our team of experts brings 50+ years of experience, a passion for innovation, and a commitment to delivering actionable insights.

Initial Discussions:
Understanding your requirements

Send us your compounds of interest

Project kick-off:
Execute with Expertise

Report delivery:
High quality reports with actionable insights