![Microfluidics chip full organism testing Organism-on-Chip Technology](https://nagibio.ch/wp-content/uploads/2023/02/organism-on-chip.jpg)
Organism-on-chip technology
in vivo testing at the in vitro scale
INTRODUCING THE FIRST ORGANISM-ON-CHIP TECHNOLOGY
ENABLING 3rs FULL-ORGANISM TESTING
Automated end-to-end culture, treatment, imaging and analysis
SydLab™ One combines the unique Organism-on-Chip technology with robotics and high-content imaging to make all the C. elegans experimentation processes automated.
![tick icon gradient](https://nagibio.ch/wp-content/uploads/2023/03/tick-icon-good-one.png)
Patented MWM technology
Thanks to the development of our patented Microfluidic Worm Matrices (MWM) technology, we offer the possibility of confining worms within large arrays of microfluidic chambers in a simple, fast and reproducible way, by means of passive hydrodynamic worm-valves.
![tick icon gradient](https://nagibio.ch/wp-content/uploads/2023/03/tick-icon-good-one.png)
First Organism-on-chip
By the usage of our MWM method, the Nagi team was eble to develop a myth that today is a reality: the first Organism-on-Chip technology for the controlled growth of C. elegans and their automated time-resolved treatment and analysis, throughout their entire lifespan.
Inside the nagi chips
discover the secrets of the first organism-on-chip
No more messy plates. No more manual handling. Unlock the full potential of small organisms with the microfluidic Nagi™ Chips. More parallel conditions, more readouts, more possibilities. All compatible with the SydLab™ One products.
![Organism-on-Chip Technology nagi chips](https://nagibio.ch/wp-content/uploads/2023/03/chip-characteristics-1-edited.png)
Sydlab™ One: One device. infinite possibilities.
Get whole-organism readouts like never before
SydLab™ One can run tests on up to four Nagi™ Chips in parallel, where 1000+ individual micro-organisms are automatically confined, cultured, treated, and studied via time-lapse microscopy images and videos at unprecedented throughput and over long-term time-resolved experiments.
Combining cutting-edge high-content screening technology and robotics, SydLab™ One is the first all-in-one benchtop laboratory device capable of performing multiple bioassays and wide screenings of your compounds of interest on micro-organisms.
Brightfield imaging
![Brightfield image of C. elegans worms taken by the SydLab System Organism-on-Chip Technology](https://nagibio.ch/wp-content/uploads/2023/03/1-4.png)
Fluorescence imaging
![Fluorescence image of a C. elegans human model worm taken by the SydLab System Organism-on-Chip Technology](https://nagibio.ch/wp-content/uploads/2023/03/1-2-1.png)
MotilitY videos
Explore the data
whole-organism phenotypic readouts instantly
SydLab™ One solution counts with the AI-powered imaging extraction and real-time SydLab™ Analyzer: a software suite trained to support scientists at every step of the process. From experiment design to readouts extraction, all in just a user optimized software.
Welcome to the era of automated multi-phenotypic data extraction, analysis and interpretation on small organisms.
nagi Resources
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Publication
Integrated Microfluidic Device for Drug Studies of Early C. elegans Embryogenesis.
Journal: Advanced Science
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Publication
Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models.
Journal: Molecular Neurodegeneration
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Publication
An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging.
Journal: Scientific Reports
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Publication
A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans.
Journal: Nature Protocols
Meet our technology here
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European Worm Meeting 2024
1 Jul 24European Worm Meeting 2024
1 Jul 24We are thrilled to announce our participation at the European Worm Meeting 2024, a central gathering for researchers across various C. elegans research domains, held in Utrech from 1st to 3rd July. Join us there, where we will showcase our pioneering C. elegans lab-on-a-device SydLab™ One through a dedicated booth, and live demonstrations. This all-in-one device is setting new standards in automated C. elegans experimentations from culture all the way down to data analysis, offering higher data accuracy, manual handling while reducing costs. Come and visit our booth, attend our multiple demonstration sessions, and explore potential collaborations to revolutionize your research approaches. #inwormwetrust
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Swiss 3Rs Day 2024
13 Jun 24Swiss 3Rs Day 2024
13 Jun 24Meet Nagi and immerse yourself in the future of ethical scientific research at the Swiss 3Rs Day on June 13th, 2024, at the AGORA Cancer Research Centre in Lausanne. This year, the 3Rs principle (Replacement, Reduction, and Refinement) in animal research have a special focus on oncology. We are excited to announce our active participation, where we will showcase our innovative approach to animal testing alternatives through our SydLab™ One device. Don’t miss the opportunity to explore our booth, engage in insightful conversations with our experts, and witness a demonstration of our cutting-edge technology that not only adheres to the 3Rs principles but contributes to the acceleration of oncology research.
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BIO International Convention 2024
3 Jun 24BIO International Convention 2024
3 Jun 24BIO International Convention 2024 is the global event for the biotechnology industry, offering a prime opportunity for professionals across the biotech industry and pharma to foster collaborations that drive innovation. Meet Nagi Bioscience at BIO from 3rd to 6th June in San Diego, California. Discuss with us how our SydLab™ One technology can streamline your research processes enhancing both cost-effectiveness and data precision. Meet us at the Swiss Pavilion and let’s explore potential collaborations that could transform your biotechnological research and development.