Early in vivo insights into UpFiber® Beta-Glucan targeting healthy aging Yeastup AG, a food tech company developing functional ingredients from brewer’s spent yeast, transforms brewery by-products into high-value yeast-derived proteins and fibers for functional ingredients. With Nagi’s SydLab™ One platform and Nagi™ B-Age AI-based assay, Yeastup AG evaluated the functional impact of a yeast-derived beta-glucan…
Many studies have focused on the key effects of specific diets and nutrients on longevity, with increasing interest in probiotic supplementation. It has been shown that living probiotics are beneficial to human health by improving intestinal microbial balance, enhancing immune modulation, and/or competing with pathogens. Using the SydLab™ One platform, we explored the effects of…
Combine lifespan, healthspan, and biological age measurements in a single experiment. Discover a smarter way to accelerate nutraceutical innovation. At Nagi Bioscience, we fast-track the development of healthy aging products through our multi-endpoint strategy, combining lifespan, healthspan, and biological age measurements in a single automated experiment. Our AI-driven Nagi™ C-Age and B-Age assays deliver translational…
Insights from C. elegans screening with SydLab™ One Discover how ElixIRA Pharma leveraged high-throughput in vivo screening to evaluate the synergistic effects of two compounds (E1 and E2) on lifespan, motility, and biological age, using automated and AI-driven analysis. What you’ll learn: How integrating phenotypic readouts early can de-risk candidate selection by identifying efficacy and…
Alzheimer’s disease (AD), the most common form of dementia, is an age-related disease strongly associated with mitochondrial dysfunction and metabolic imbalance, both of which accelerate cellular and neuronal decline. Mitochondrial dysfunction, such as mitochondrial hypermetabolism, has been identified as a critical event in the onset and progression of AD. In parallel, caloric restriction (CR) stands…
𝖶𝗁𝖺𝗍 𝗂𝖿 𝗐𝖾 𝖼𝗈𝗎𝗅𝖽 𝗆𝖾𝖺𝗌𝗎𝗋𝖾 𝖻𝗂𝗈𝗅𝗈𝗀𝗂𝖼𝖺𝗅 𝖺𝗀𝖾, 𝗁𝖾𝖺𝗅𝗍𝗁𝗌𝗉𝖺𝗇, 𝖺𝗇𝖽 𝗅𝗂𝖿𝖾𝗌𝗉𝖺𝗇 𝖺𝗅𝗅 𝖺𝗍 𝗈𝗇𝖼𝖾? Learn how experts are transforming the way we discover interventions in aging and neurodegeneration in our webinar. Join us for a thought-provoking 40-minutes session where leading experts will share cutting-edge insights at the intersection of fundamental science and translational innovation: Prof. Konstantinos…
Explore how to combine lifespan, healthspan, and biological age measurements in a single experiment. What to expect from this snapshot guide: Current challenges in longevity and aging research: Bringing interventions from the lab to the market. A multi-endpoint, one-shot approach: lifespan, healthspan, and biological age measurements at once. Applying C-Age and B-Age assays: Doxycycline interventions.…
Nagi™ B-Age is a fully automated, AI-powered assay that measures biological age in C. elegans using high-content images acquired through the SydLab™ One platform. This multiparametric approach evaluates over 20 phenotypic biomarkers to assess five vital traits. These traits represent how the organism allocates energy across its lifespan. The biological age values are computed for…
High-throughput analysis is a challenge in C. elegans research. One example is the conduction of lifespan assays that rely on heavy manual work for a long period of time. In response, we devel- oped a robotic microfluidic-based platform, the SydLab™ One, capable of handling culture, treatment, and imaging of up to 64 worm populations in…