𝖶𝗁𝖺𝗍 𝗂𝖿 𝗐𝖾 𝖼𝗈𝗎𝗅𝖽 𝗆𝖾𝖺𝗌𝗎𝗋𝖾 𝖻𝗂𝗈𝗅𝗈𝗀𝗂𝖼𝖺𝗅 𝖺𝗀𝖾, 𝗁𝖾𝖺𝗅𝗍𝗁𝗌𝗉𝖺𝗇, 𝖺𝗇𝖽 𝗅𝗂𝖿𝖾𝗌𝗉𝖺𝗇 𝖺𝗅𝗅 𝖺𝗍 𝗈𝗇𝖼𝖾? Learn how experts are transforming the way we discover interventions in aging and neurodegeneration in our webinar. Join us…
Explore how to combine lifespan, healthspan, and biological age measurements in a single experiment. What to expect from this snapshot guide: Current challenges in longevity and aging research: Bringing interventions from the…
Nagi™ B-Age is a fully automated, AI-powered assay that measures biological age in C. elegans using high-content images acquired through the SydLab™ One platform. This multiparametric approach evaluates over 20 phenotypic biomarkers…
High-throughput analysis is a challenge in C. elegans research. One example is the conduction of lifespan assays that rely on heavy manual work for a long period of time. In response, we…
As aging research remains at the forefront of biomedical science and an increasingly growing social issue, understanding the biological mechanisms behind cellular and organismal decline is crucial to extending healthspan — the…
Dysfunction of Paneth and goblet cells in the intestine contributes to inflammatory bowel disease (IBD) and colitis-associated colorectal cancer (CAC). Here, we report a role for the NAD+-dependent histone deacetylase SIRT1 in…
In recent years, tetracyclines, such as doxycycline, have become broadly used to control gene expression by virtue of the Tet-on/Tet-off systems. However, the wide range of direct effects of tetracycline use has…
The biological effects of urolithins remain poorly characterized, despite wide-spread human exposure via the dietary consumption of their metabolic precursors, the ellagitannins, which are found in the pomegranate fruit, as well as…
Mitohormesis defines the increase in fitness mediated by adaptive responses to mild mitochondrial stress. Tetracyclines inhibit not only bacterial but also mitochondrial translation, thus imposing a low level of mitochondrial stress on…