Aging researchHealthspan & Lifespan

2025

Application NotesApplication Notes

Nagi™ B-Age: Biological age measurements for anti-aging interventions

Nagi™ B-Age is a fully automated, AI-powered assay that measures biological age in C. elegans using high-content images acquired through the SydLab™ One platform. This multiparametric approach evaluates over 20 phenotypic biomarkers to assess five vital traits. These traits represent how the organism allocates energy across its lifespan. The biological age values are computed for each trait, and then integrated into a single, comprehensive biological age for the organism.

Nagi™ B-Age offers a powerful and scalable solution for measuring biological age in C. elegans, providing a high-resolution, phenotypic readout that captures the complexity of aging beyond what chronological time alone can reveal. By quantifying the biological age of five vital traits, it enables a detailed understanding of how different interventions impact the aging process at a functional level.

Whether assessing combinations of known longevity compounds or exploring novel molecules, testing interventions late in life, or modeling accelerated aging, Nagi™ B-Age provides a unique platform to screen, compare, and prioritize anti-aging interventions with unprecedented precision and speed. Its full automation and in vivo relevance, provides an essential set of results for advancing the discovery of interventions that promote healthy aging and longer life.