Study the Biology of Aging

Nagi Bioscience banner promoting tools to study the biology of aging through translational, automated, and high-throughput in vivo research with C. elegans models.

The Challenge

Aging is the single greatest risk factor for chronic disease, yet its underlying biological mechanisms remain only partially understood.

Researchers face the dual challenge of complex biology and limited tools: conventional models are either too simplistic (in vitro) or too resource-intensive and ethically constrained (vertebrates).

This gap slows the generation of mechanistic insights and limits our ability to translate discoveries into meaningful interventions.

Key trends

The biology of aging is now recognized as a cornerstone of medicine, with nine hallmarks of aging serving as a framework for global research.

The average C. elegans lifespan is only 2–3 weeks, making it a proven model to accelerate the study of conserved aging pathways.

There is a unique opportunity to decode the mechanisms of aging with tools that combine the speed of invertebrate models with the rigor of high-throughput, quantitative science.

This opens the door to deeper mechanistic understanding, collaborative projects, and faster translation into biomedical innovation.

Streamlining C. elegans research with automation, reproducibility, and high-throughput

A Powerful in vivo Model

C. elegans is a transparent, genetically tractable organism with conserved aging pathways that mirror human biology, enabling real-time studies of mitochondrial function, stress response, proteostasis, and autophagy.

C. elegans has served as a rapid in vivo platform for mechanistic insights and drug discovery for over 60 years and has been recognized with 4 Nobel Prizes.

Automation and Reproducibility

Our SydLab One platform eliminates the variability of manual experiments.

With automated handling and AI-driven analytics, researchers gain consistent, reproducible datasets that accelerate discovery and support publication-quality results.

Multi-Phenotypic and Mechanistic Insights

From healthspan and lifespan to advanced biological metrics like Biological Age, our system provides a holistic view of aging.

Researchers can connect interventions to mechanistic pathways, generating insights that deepen the field’s understanding of aging biology.

DTU Biosustain and Novo Nordisk Foundation logo: academic and research collaboration with Nagi Bioscience on healthy aging innovations.
National and Kapodistrian University of Athens NKUA logo: Medical Faculty Palikaras research group advancing mechanisms of aging and neurodegeneration with support from Nagi Bioscience. Discovering combined interventions against Alzheimer's Disease.
Harvard T.H. Chan School of Public Health logo: leading academic institution leveraging Nagi Bioscience platform SydLab One for aging biology research and metabolism and diet.
ICMAB Institut de Ciència de Materials de Barcelona logo: microplastics ecotoxicology supported by Nagi Bioscience technology.
ERIBA logo: Representing collaboration with Nagi Bioscience in translational programs for neurodegenerative diseases with academic research groups on the biology of aging.
EPFL logo: Representing academic collaboration in longevity and aging biology research and where Nagi Bioscience was born with breakthroughs like Urolothin A or NAD+ pathways.

Recent Projects

Nagi Snapshot Guide: maximizing translational value in aging research by combining lifespan, healthspan, and biological age measurements in one automated in vivo experiment.
Scientific publication on Cell highlighting NAD⁺ and sirtuin pathways in longevity and mitochondrial function for aging research validation. Powered by Nagi Bioscience, being its first author Nagi Bioscience's CSO Laurent Mouchiroud.
Case study on caloric restriction (CR) and Alzheimer’s disease progression using Nagi Bioscience’s SydLab™ One and Nagi™ B-Age platforms. Research with C. elegans models from Prof. Palikaras’ lab shows CR improves lifespan, healthspan, motility, and reduces biological age in wild-type and tau40-expressing nematodes, highlighting the role of mitochondrial function in aging and neurodegeneration.

With Nagi Bioscience, you gain:

Obtain Biological Age and health-span data in just 10 days; lifespan results in ~20 days.

Screen and expand experimental your scope.

Access pathway-specific insights that strengthen hypotheses and enhance publication impact.

Simplify complex worm biology workflows, even for non-specialists, with a fully automated, user-friendly platform.

Generate robust datasets that support grants, partnerships, and translational projects.

From teaching labs to cutting-edge research groups, Nagi Bioscience enables academia to decode the mechanisms of aging with speed, precision, and reproducibility.

Drive new discoveries that shape the future of biomedical science.

National and Kapodistrian University of Athens NKUA logo: Medical Faculty Palikaras research group advancing mechanisms of aging and neurodegeneration with support from Nagi Bioscience. Discovering combined interventions against Alzheimer's Disease.

By improving precision and enhancing reproducibility, SydLab™ One empower us to explore new frontiers in critical fields of medical science. We are excited to leverage this fully automated, end-to-end solution in our projects and accelerate the pace of scientific discovery.

DTU Biosustain and Novo Nordisk Foundation logo: academic and research collaboration with Nagi Bioscience on healthy aging innovations.

“Their services revealed new insights and opened up exciting possibilities for exploring the potential of our strains in health applications related to healthy aging, helping us advance our research further.

Immunic Therapeutics logo: biotech company advancing immune and neurodegenerative therapeutics with support from Nagi Bioscience.

We had a highly positive experience with Nagi’s services. Their innovative assays provided a reliable alternative to mouse studies by leveraging the short lifespan of C. elegans and the high conservation of our target from worms to human.