Assess developmental & reproductive toxicity
with confidence
Nagi™ DART provides automated, fast and scalable in vivo toxicity profiling at the in vitro scale, enabling earlier identification of potential risks.
Automated
end-to-end
From age-synchronized nematodes to data analysis, no manual handling.
High-content longitudinal data
Track development, reproduction and multiple phenotypes over time for rich, dynamic biological insights.
AI-powered
Analytics
Advanced algorithms turn complex data into clear, actionable insights.
An In Vivo Fast and Relevant Model
C. elegans: a whole organism model with conserved biological pathways.
Physiologically Relevant and Ethical
A NAMs model recognized by the FDA, now at scale.
THE Nagi™ lifespan WORKFLOW
From compounds to clear answers
Age-synchronized populations of C. elegans are injected into the NAGI™ microfluidic chips and exposed to your compounds in a fully automated workflow on SydLab™ One.
The platform will expose each nematode population to your environment of choice (temperature, feeding and treatment) while high-content imaging captures longitudinal data without manual handling.
A faster, predictive way to evaluate developmental and reproductive toxicity
C. elegans offers a unique combination of short life cycle, genetic tractability and conserved pathways, making it an ideal NAMs model to rapidly assess the impact of your compounds during developmental and reproductive period.
- Earlier decision-making in compound development.
- Reduce reliance on vertebrate models.
- Detect subtle developmental and reproductive effects thanks to AI analytics.
Reliable, reproducible data
Prioritize your candidates with confidence
NAGI™ DART generates robust, dose-response data and detailed toxicity profiles, enabling clear identification of NOAEL and compound-specific effects across multiple generations.
Multi-phenotypic analysis: Paraquat
Multi-phenotypic analysis: 5-FU
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