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  • On-chip microfluidic biocommunication assay for studying male-induced demise in C. elegans hermaphrodites.

    Like other animals, C. elegans nematodes have the ability to socially interact and to communicate through exchange and sensing of small soluble signaling compounds that help them cope with complex environmental conditions….

    March 13, 2023
  • Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans.

    In a typical high-throughput drug screening (HTS) process, up to millions of chemical compounds are applied to cells cultured in well plates, aiming to find molecules that exhibit a robust dose-response, as…

    March 13, 2023
  • Integrated Microfluidic Device for Drug Studies of Early C. elegans Embryogenesis.

    Small molecules inhibitors are powerful tools for studying multiple aspects of cell biology and stand at the forefront of drug discovery pipelines. However, in the early Caenorhabditis elegans (C. elegans) embryo, which…

    March 13, 2023
  • Microfluidic system for Caenorhabditis elegans culture and oxygen consumption rate measurements.

    Mitochondrial respiration is a key signature for the assessment of mitochondrial functioning and mitochondrial dysfunction is related to many diseases including metabolic syndrome and aging-associated conditions. Here, we present a microfluidic Caenorhabditis…

    March 13, 2023
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