Many studies have focused on the key effects of specific diets and nutrients on longevity, with increasing interest in probiotic supplementation. It has been shown that living probiotics are beneficial to human health by improving intestinal microbial balance, enhancing immune modulation, and/or competing with pathogens.
Using the SydLab™ One platform, we explored the effects of the living probiotic Lactobacillus rhamnosus GG (LGG) on the physiological functions of C. elegans, including lifespan and health biomarkers like mobility and reproduction. Additionally, we deployed Nagi™ B-Age to assess the impact of the LGG strain on the overall biological age of the nematode. We selected Lactobacillus rhamnosus GG (LGG), an FDA-recognized probiotic strain widely used in dietary supplements and fermented foods for its gastrointestinal and immune benefits. Emerging evidence suggests LGG’s positive effects on urinary infections and vaginal microbiota.