<img src="/themes/nagibioscience/logo.svg" alt="Nagi Bioscience" class="brand__logo"/>

Laurent Mouchiroud, Elena Katsyuba, David Liaskos, David Rouquié, Ainhoa Letamendia, Matteo Cornaglia

Fully automated laboratory device for aging studies using the nematode Caenorhabditis elegans.

David Liaskos, Elena Katsyuba, Laurent Mouchiroud, Johan Auwerx, Matteo Cornaglia

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.

Journal: EMBO Journal Publication

Ramanath Narayana Hegde, Anass Chiki, Lara Petricca, Paola Martufi, Nicolas Arbez, Laurent Mouchiroud […] Hilal Lashuel

An in vivo microfluidic study of bacterial transit in C. elegans nematodes.

Vittorio Viri, Matteo Cornaglia, Huseyin Baris Atakan, Thomas Lehnert, Martin Gijs

Microfluidic system for Caenorhabditis elegans culture and oxygen consumption rate measurements.

Roger Krenger, Matteo Cornaglia, Thomas Lehnert, Martin Gijs

Worm-on-a-chip technology: An emerging 3R model in toxicity testing.

Carole Mathis, Laurent Mouchiroud, Matteo Cornaglia, Daniel Smart, Mohamed Amin Choukrallah, Karsta Luettich, Julia Hoeng, Manuel Peitsch

Automated high-content phenotyping of the nematode Caenorhabditis elegans: application to the toxicity assessment of perovskites.

Laurent Mouchiroud, Matteo Cornaglia, Alix Pham, Josipa Scurla […] Martin Gijs

Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans.

Huseyin Baris Atakan, Matteo Cornaglia, Laurent Mouchiroud, Johan Auwerx, Martin Gijs

Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution.

Journal: Microsystems & Nanoengineering Publication

Maria Cristina Letizia, Matteo Cornaglia, Raphaël Trouillon, Vincenzo Sorrentino, Laurent Mouchiroud, Maroun Bou Sleiman, Johan Auwerx, Martin Gijs

Integrated Microfluidic Device for Drug Studies of Early C. elegans Embryogenesis.

Journal: Advanced Science Publication

Li Dong, Radek Jankele, Matteo Cornaglia, Thomas Lehnert, Pierre Gönczy, Martin Gijs

Reversible and long-term immobilization in a hydrogel-microbead matrix for high-resolution imaging of Caenorhabditis elegans and other small organisms.

Journal: PLoS One Publication

Li Dong, Matteo Cornaglia, Gopalan Krishnamani, Jingwei Zhang, Laurent Mouchiroud […] Martin Gijs

Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity.

Journal: Nature Publication

Vincenzo Sorrentino, Mario Romani, Laurent Mouchiroud, John Beck, Hongbo Zhang […] Johan Auwerx

Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans.

Matteo Cornaglia, Thomas Lehnert, Martin Gijs

Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.

Journal: FASEB Journal Publication

Sarah Preston, Pasi Korhonen, Laurent Mouchiroud, Matteo Cornaglia, Sean McGee, Neil Young […] Robin Gasser

Worm-on-Chip: fully automated whole-organism platform for screening and identification of toxicity using the nematode Caenorhabditis elegans.

Laurent Mouchiroud, Matteo Cornaglia, Robert Mader, Martin Gijs, Johan Auwerx

On-chip microfluidic biocommunication assay for studying male-induced demise in C. elegans hermaphrodites.

Li Dong, Matteo Cornaglia, Thomas Lehnert, Martin Gijs

NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.

Journal: Science Translational Medicine Publication

Dongryeol Ryu, Hongbo Zhang, Eduardo Ropelle, Vincenzo Sorrentino, Davi Mázala, Laurent Mouchiroud […] Johan Auwerx

A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans.

Journal: Nature Protocols Publication

Mandy Koopman, Helen Michels, Beverley Dancy, Rashmi Kamble, Laurent Mouchiroud […] Riekelt H Houtkooper

The Movement Tracker: A Flexible System for Automated Movement Analysis in Invertebrate Model Organisms.

Journal: Current Protocols in Neuroscience Publication

Laurent Mouchiroud, Vincenzo Sorrentino, Evan Williams, Matteo Cornaglia, Michael Frochaux […] Johan Auwerx

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents.