Biological Age

2026

Technical NotesTechnical Notes

NAGI™ Biological Age : Phenotypic biological age measurements for healthy aging interventions

A multi-dimensional biological age framework that moves beyond a single aging score.

NAGI™ Biological Age is an AI-powered phenotypic biological age assessment solution that enables longitudinal, non-invasive quantification of biological aging using C. elegans, a cornerstone organism in aging research. Built on the Nagi Bioscience SydLab™ One automated microfluidic imaging platform, NAGI™ Biological Age combines high-content brightfield imaging, state-of-the-art computer vision, and AI to generate an interpretable assessment of organismal health throughout life.

The analysis is organized into three complementary layers of biological insight:

  • Overall Biological Age, providing an integrated measure of organismal aging.
  • Systems & Organization, identifying the biological age contribution of major physiological systems, including neuromuscular function, digestive system, reproductive system, body size, and structural integrity.
  • Organs & Functions, offering biological age measurements of individual organs and functional biomarkers that further dissect the biological age prediction.