Resources

Publication
A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.

Author list:
Pénélope Andreux, Laurent Mouchiroud, Xu Wang, Virginija Jovaisaite, Adrienne Mottis […] Johan Auwerx

Journal: Scientific Reports
Publication
Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.

Author list:
Eija Pirinen, Carles Cantó, Young Suk Jo, Laia Morato, Hongbo Zhang, Keir Menzies, Evan Williams, Laurent Mouchiroud […] Johan Auwerx

Journal: Cell Metabolism
Publication
Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans.

Author list:
Huseyin Baris Atakan, Matteo Cornaglia, Laurent Mouchiroud, Johan Auwerx, Martin Gijs

Journal: Lab on a Chip
Publication
Reversible and long-term immobilization in a hydrogel-microbead matrix for high-resolution imaging of Caenorhabditis elegans and other small organisms.

Author list:
Li Dong, Matteo Cornaglia, Gopalan Krishnamani, Jingwei Zhang, Laurent Mouchiroud […] Martin Gijs

Journal: PLoS One
Publication
Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution.

Author list:
Maria Cristina Letizia, Matteo Cornaglia, Raphaël Trouillon, Vincenzo Sorrentino, Laurent Mouchiroud, Maroun Bou Sleiman, Johan Auwerx, Martin Gijs

Journal: Microsystems & Nanoengineering
Publication
NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.

Author list:
Hiroyasu Yamamoto, Evan G Williams, Laurent Mouchiroud, Carles Cantó, Weiwei Fan, Michael Downes […] Johan Auwerx

Journal: Cell
Publication
The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.

Author list:
Laurent Mouchiroud, Riekelt Houtkooper, Norman Moullan, Elena Katsyuba, Dongryeol Ryu […] Johan Auwerx

Journal: Cell
Publication
An in vivo microfluidic study of bacterial transit in C. elegans nematodes.

Author list:
Vittorio Viri, Matteo Cornaglia, Huseyin Baris Atakan, Thomas Lehnert, Martin Gijs

Journal: Lab on a Chip
Publication
NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.

Author list:
Dongryeol Ryu, Hongbo Zhang, Eduardo Ropelle, Vincenzo Sorrentino, Davi Mázala, Laurent Mouchiroud […] Johan Auwerx

Journal: Science Translational Medicine
Publication
Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models.

Author list:
Matteo Cornaglia, Gopalan Krishnamani, Laurent Mouchiroud, Vincenzo Sorrentino, Thomas Lehnert, Johan Auwerx, Martin Gijs

Journal: Molecular Neurodegeneration
Publication
An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging.

Author list:
Matteo Cornaglia, Laurent Mouchiroud, Alexis Marette, Shreya Narasimhan, Thomas Lehnert, Virginija Jovaisaite, Johan Auwerx, Martin Gijs

Journal: Scientific Reports
Publication
An evolutionarily conserved role for the aryl hydrocarbon receptor in the regulation of movement.

Author list:
Evan Williams, Laurent Mouchiroud, Michael Frochaux, Ashutosh Pandey, Pénélope Andreux, Bart Deplancke, Johan Auwerx

Journal: PLoS Genetics

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Resources

A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.

Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.

Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans.

Reversible and long-term immobilization in a hydrogel-microbead matrix for high-resolution imaging of Caenorhabditis elegans and other small organisms.

Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution.

NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.

An in vivo microfluidic study of bacterial transit in C. elegans nematodes.

NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.

Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models.

An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging.

An evolutionarily conserved role for the aryl hydrocarbon receptor in the regulation of movement.

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