Resources

Publication
The Movement Tracker: A Flexible System for Automated Movement Analysis in Invertebrate Model Organisms.

Author list:
Laurent Mouchiroud, Vincenzo Sorrentino, Evan Williams, Matteo Cornaglia, Michael Frochaux […] Johan Auwerx

Journal: Current Protocols in Neuroscience
Publication
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents.

Author list:
Dongryeol Ryu, Laurent Mouchiroud, Pénélope Andreux, Elena Katsyuba, Norman Moullan, Amandine Nicolet-Dit-Félix […] Johan Auwerx

Journal: Nature Medicine
Publication
Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.

Author list:
Carsten Merkwirth, Virginija Jovaisaite, Jenni Durieux, Olli Matilainen, Sabine Jordan, Pedro Quiros, Kristan Steffen, Evan Williams, Laurent Mouchiroud […] Andrew Dillin

Journal: Cell
Publication
Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research.

Author list:
Norman Moullan, Laurent Mouchiroud, Xu Wang, Dongryeol Ryu, Evan Williams, Adrienne Mottis […] Johan Auwerx

Journal: Cell Reports
Publication
A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.

Author list:
Pénélope Andreux, Laurent Mouchiroud, Xu Wang, Virginija Jovaisaite, Adrienne Mottis […] Johan Auwerx

Journal: Scientific Reports
Publication
Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.

Author list:
Eija Pirinen, Carles Cantó, Young Suk Jo, Laia Morato, Hongbo Zhang, Keir Menzies, Evan Williams, Laurent Mouchiroud […] Johan Auwerx

Journal: Cell Metabolism
Publication
Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans.

Author list:
Huseyin Baris Atakan, Matteo Cornaglia, Laurent Mouchiroud, Johan Auwerx, Martin Gijs

Journal: Lab on a Chip
Publication
Reversible and long-term immobilization in a hydrogel-microbead matrix for high-resolution imaging of Caenorhabditis elegans and other small organisms.

Author list:
Li Dong, Matteo Cornaglia, Gopalan Krishnamani, Jingwei Zhang, Laurent Mouchiroud […] Martin Gijs

Journal: PLoS One
Publication
Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution.

Author list:
Maria Cristina Letizia, Matteo Cornaglia, Raphaël Trouillon, Vincenzo Sorrentino, Laurent Mouchiroud, Maroun Bou Sleiman, Johan Auwerx, Martin Gijs

Journal: Microsystems & Nanoengineering
Publication
NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.

Author list:
Hiroyasu Yamamoto, Evan G Williams, Laurent Mouchiroud, Carles Cantó, Weiwei Fan, Michael Downes […] Johan Auwerx

Journal: Cell
Publication
The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.

Author list:
Laurent Mouchiroud, Riekelt Houtkooper, Norman Moullan, Elena Katsyuba, Dongryeol Ryu […] Johan Auwerx

Journal: Cell
Publication
An in vivo microfluidic study of bacterial transit in C. elegans nematodes.

Author list:
Vittorio Viri, Matteo Cornaglia, Huseyin Baris Atakan, Thomas Lehnert, Martin Gijs

Journal: Lab on a Chip

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Keen to hear about the latest news in the world of alternative testing methods? Are you interested in learning about the latest techniques in toxicology? Maybe a worm enthusiast?

Resources

The Movement Tracker: A Flexible System for Automated Movement Analysis in Invertebrate Model Organisms.

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents.

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.

Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research.

A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.

Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.

Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans.

Reversible and long-term immobilization in a hydrogel-microbead matrix for high-resolution imaging of Caenorhabditis elegans and other small organisms.

Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution.

NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.

An in vivo microfluidic study of bacterial transit in C. elegans nematodes.

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